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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd064cf90b049b73c1d4e56973d699f6f22e84f9e3f1ded43280c18d272a43317' 
  AND token = 'GnxdRd040pPK0w38eLBrruwDw0Dz5G8ho7uv+NckeyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}