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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77e6334c63900c0d2b1c049a0c9e98850ea141ce1bfbd6a325d42dab0ca2d35' 
  AND token = 'pbbmOlCyItwjDoC2+TDmu0EazkZEV+UlM+TVhFIMj0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}