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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40a331f67c586a934cf9c2219cd7f27708cefa39b219c85c7a10e713e8127012' 
  AND token = '8fNG1pECVt5v7OJ/H4zCGK/1AxLfPm4PzckEwgBmUMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}