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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e340a546a4580704241e97e7d151da53b9fa467770012f7162e4eef8bcafc80' 
  AND token = 'em/uywprnOLc6tgOMXXApSKsZds9qXw/p+Fyte8KOjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}