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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f59be6eb1cb3af5e3229e43b37fccadc2f2c9a50020f202e8109a9701863630' 
  AND token = '9McxWMzO5R1oICWl4WgzENqJCSOGqbBL3k/WzZo0MXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}