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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2651ef3bea3c72f6cd49a441dec2f863e3dfa1aa713b10bd71756d37c939b09a' 
  AND token = 'n0M6/Dj5NIHy9+8sE6B89W2nAxSweAwrsOOs7Y3OV2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}