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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1355db087acba3869087a6168afd05c80994144e34a781cefbf1c89c0b45365c' 
  AND token = '52UIXcODcDMBDZLQBJyyy1eVu8GH3Vy+tIGm0gWO8Ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}