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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343211115e31fc5ebcf12fee6f1fa98b45b8ff02f673ec77ee14626d8a475427' 
  AND token = 'bQjYsinxI7ylnRN1bB1lhIk7mOZ1rjNUBx8kyPS53Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}