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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c15f76b5a1daf1db9538ed2d2ed5a40239bcd8095a2f2bef73291d4dabec85' 
  AND token = 'HXJDo2+S/Rk/mz+tNqY2BxxatcIptbOe1rJSW6AjdOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}