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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b8e7453102bb4db94f1d3778ce6fa0e34ec225dad056a190783935608a20081' 
  AND token = 'tI/bYQInhGDehtNW9gbpP6QO6y4g0nqN4/G6LjYX+Cw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}