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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a8e7db1122ba8cf49c1a951deed3b013658bb05e1a918b7235d62ada6525cc' 
  AND token = 'aKo73uMpN/CC5peZ90+SFdCU+pzZWHRFVyDv6cx0GZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}