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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca321aba7b436a4eda52e5ed67f94feb8d787ca93f0fd19ab1ddffb2cb3aca2' 
  AND token = 'ZZGp6474kYJfDV4XRkDfaYVGqN5qhdNrAR/UR/7O7mM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}