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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f2312d20041a1ffb7e79e8b1925647a107b6a61bc6429f654b479f9a2c8da19' 
  AND token = 'QAvIFPoxtIH3/72jFYxaC4OKBuCg3XaQntmB22a603k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}