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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b45db4aa34738e70dc0e2bee371bf9596d96fb0686280aeb816b33a93aa0d991' 
  AND token = 'pr6CZnFNRQxn5K4cTVT1UbXx14GWZyQ1HW/dmwk+yXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}