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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42e60639e4b95bb2528e813a03e7a26d3e2828b4365f29d793e30d66abfabe49' 
  AND token = 'vxoZ5Qg2d6R/ZyV8DQ/geDoi1YqICu+Ewxv54ndtFfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}