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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12e52f83d9d7c5d46b8a9b66835b79a15547d63b09b4b29a091697800c3bce2' 
  AND token = 'dvBtmj465Nce7/JoRajaBOk/LPbfGxgGcRHRBVJTpWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}