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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0094edc6e4dd0bde5cbbd47de36e3f62d24b330de9aaae6b713bb22d92dc0a' 
  AND token = 'IioSA5D7WEL/sq0AnGjjT5o6kYMg+Zz9M+Z0el76JVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}