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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443751d21d9b4c8f91236a18cd4b3df564c5fa11f883ec247825f663f7b66682' 
  AND token = 'v8PzhGG7L4b1W0gAfqXE/yPA93MHFb99s2XQrHO1Qho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}