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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7e2f2f677935782878b8e4ecedc7796ab094a3d8f3fc53cc6364f946afe346b' 
  AND token = 'U+G8nrL0/AOk0VUtMbkpnl0fxC4zEqd1CcTEGz8zdNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}