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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6415358473c1bbe5060958d0b797091ddc868e2672b096950d47d206ed014fd2' 
  AND token = 'rMeBLgRQfKiHX6FJ9GY27NtlGL6OxC3oLsD+4y+KtN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}