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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ccb1f5a5983353b7070d90c32e18faa15fe5146a3ca1c477c667cdc2019681c' 
  AND token = 'JD2rouagVPtLgBBDdJaNHes2syMOMrU39kiKb4oR7Js=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}