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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac9f3f03038fdcc64615f28c788a464d3d014a4c019474060cec6a76db4a5dc' 
  AND token = 'c6qsevUtMmSBVGRfT98qaQND13YMr0HXh8SL+CmqK80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}