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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ce93e2c8a8c71fdcd346d5db647bbbdec91f4fafbdb6d847fc4c09e68b74a04' 
  AND token = 'n6C/6RM/iGbqC/vCeqSulxf/1RmaAsJx3mj0U5x0rvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}