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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d735bcff7c8c707fd818b081d8b8b4fede7c030917e59e7da792de97bf41c2' 
  AND token = 'ZVmLyi0RbFNjQ5NCudNjg3i1HTfTGHNJXNeuPDCtp7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}