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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb161065d576ee45d6c62fa47f32af54afaa628b8eee3661eee41b2fd02b0e1' 
  AND token = 'si1SJUeRnCWE4j0djH0314at3w7jMPnk7WwSZCNJVjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}