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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331f257008e182cde69fdb2f488088452ab15f30d4e08e155e17fd7d7c1a1dc1' 
  AND token = 'rYh/4tcfcZNE4j//ngwGm4KX8Vx2e5IMRm9teg5Mx6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}