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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493c57f74e3b3edbf6b64cbd32b64489a7358893f3e889be72013abfa5dae2a1' 
  AND token = '5kGABkE0KhfewvZ+TDc8NosQQdx/aftUElJMn00xyjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}