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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6426381ce4d07bb27532ea9d46a5f11e47134b7f2475cb5d4dad2a3de7df1dc' 
  AND token = 'yXdaQdQgn92GzKslxN3EK0+WaGG7qu/xuc8YncDvEHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}