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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6c2459b9b32b88caeb611cfdb5f494068608f54681e81db6f7a6522c24f0db' 
  AND token = 'SJdWIB9K8XrCQbvsxRKd8nGAqiQ2sKlGJ5MjcKWnTnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}