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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f2ca66aeec95ae5b1d9d0e28ef59886030afa448c437380907a2bc22c68890' 
  AND token = '1xU09DDIEr3H+QEEpxcbpXLgd/HJF3LLNnhlJJqeCmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}