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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8aac3c098f4cf8da1c180c614961b22b3fe6810586e47123b4ba683eca0a386' 
  AND token = 'HmxG0qLiBpRkn3s5jCDNiFYcvEaw0XvHyCK0l1w7u3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}