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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e470f2a6c6e616fe22e2b626db3b05d8282357811ac19a4357f0b8df920eaebb' 
  AND token = 'SUBu00tvgQ3jkQlPbpKBQwLiDqrCzXL5YAsR4ZAu8a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}