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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '157b49f1f3c13b2cd828970447b1c6bd9bdf4f37f53e5a37f881adcf7b819e30' 
  AND token = 'LrUvBqrZP3D87d66e4LHEyeJPn06RJxYcpIRyOdxmI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}