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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06e4f9961677e1b4c79b8c98b706d5382b5e4f88ad4e11eee996fb2df9894e9a' 
  AND token = 'NEWLTZGWwAgrlgtN7LhTAGFnXYM5PNDHFLFhMLHC0mA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}