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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6156777a8ccf9b0774f7a02456ecce9f9f60f6b691c04299935235f4d54d900' 
  AND token = 'TnQ3rbPSqZJririARfeZxdQWgXiHTCHCCv1pz3PTXaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}