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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81a2694d75d99645e9161aa5a966a5bc7c48bb5f1d8c6c8425bdac06e955cfc' 
  AND token = 'lkqfPu1HCWwfQ2y11rx+xbbNgP9MFDjj9dLm60TOqyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}