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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5611a1a71741ad0357081665255e9dd3d4c49c4f117c53925ba7e24a33079ef5' 
  AND token = 'P3TXXUoVhGZdWNYNQM2FlH146bM5zrXXm5x/WoKUZlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}