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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ffe9740c6e1ce401a56cc13d1484542781202db0db1d33feb853a76e46c9daa' 
  AND token = 'i4/wZuc/6dSwOtlhUxda7CyPPNVnEIFtKTgnC202Lak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}