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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6901d8f1c11a155e8f8b88bb7cf0f5c23693747ac321db03d84c9f3b717718e6' 
  AND token = 'TZ0iAJCssraWkv7+DiqbCBH9nl1wnO9osYsyWG1sfuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}