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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7155fc4a7e8d764cbb061648fb0da2ec0a512fe320f8a2e70b24dea2e9474af5' 
  AND token = '1W7ixKYKSJ8LsLndRP5e5zbAOaomkC0eDxNwIIUqzO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}