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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54b56df4a66348c262c7a26c9c5aab3d1f560704f59c377289acba9d1b5d46f' 
  AND token = 'GeP9+ix4EHYxzInSD0mc0VJoLhkA40y7wMwOPOVfpRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}