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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '427b750f6180943d66de0a3fe59f5197e9336828fe3c7d9a3acec1ddf15d40b4' 
  AND token = '0ckoKWAxgLRD/SNgR3CsTZSRpaXlE9KmKvbW3w1DNAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}