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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b36effc591e7b0f68416dea7f8649f8abe87b7b944f4b04eb26c2fe9120230be' 
  AND token = 'aS1OjZtAb5ZtP6hg+lsAA6iDg6waIRp+aprM3dmYEy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}