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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5caf896fa6a1aabd1fadd76b9594e32594e1c3f47b8ac95d837eb5c1a21d01a3' 
  AND token = 'P4Hjik0/YGnFw20cD50RXetRc+Tx2xgRvI4SFHXVGXk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}