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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e6ad383a810fabb7eaf3dc584a7639bdd157dc72f76f0e77ca7dc3fe011a25' 
  AND token = 'oG3c83Xu+fJIfmqiHBNh6OcN/ldi6yuchpN6T2ooH3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}