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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0453d37b12ede6d2e30ab36796379deb6b1058a0ebdd276e8e146cef6d233b4' 
  AND token = 'POtS1rSyxFLt5GUluJz+8KErUbhTKXG2ncLQ7ICDR2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}