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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5191ba0bd61e8e27aea627de9bffb27323d3d5b4e23d455e871a447c25bb63a6' 
  AND token = '/WqloDusTHLZYs0n5IqpV+6n+RR8rpBQ2ipU9BR+Tks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}