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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cd86fba8f7545635a5faa7e09d1a384b4d618ab1b4627946da279424eaec48d' 
  AND token = 'TSsYzad8RuNThMBeRWV1SiYPxgtRhSu34z1xlCdLkGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}