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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '525dba8bd4a3d1ff76a35cb03fe82337b316d2cf207e55773458e60c858bd06b' 
  AND token = 'rcdSUwA9z0x4/sNagN0Kz0vx3dqbUkk7CKRpmm8OtwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}