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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '600cdd8b34d032f61565b4728a25c6464b811c44878b21dd3cbf1003c4f21e23' 
  AND token = 'EHOUDlpog58+Yf6MhyUQxAOB+LHslY+eQ1KA3yXOnPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}